Expert Guidance on Preparation Techniques
With profound expertise in small molecule peptide preparation and bioenzyme selection, Professor Wang meticulously reviewed the company’s current production processes for donkey-hide gelatin peptides. She emphasized that optimizing preparation protocols—particularly in bioenzyme engineering—is critical to enhancing product efficacy.
Key Challenges & Innovations:
- Traditional donkey-hide gelatin products face limitations in bioavailability due to their large molecular weight.
- Dong’e Chenkang’s breakthrough lies in transforming gelatin nutrients into low-molecular-weight peptides (<1,000 Da) through advanced enzymatic hydrolysis, significantly improving absorption rates.
Professor Wang highlighted that enzyme specificity, activity parameters, and reaction conditions directly determine peptide yield and bioactivity. Her recommendations included:
- Screening thermostable proteases to enhance hydrolysis efficiency
- Adopting AI-driven enzyme-substrate matching for precision catalysis
- Implementing green chemistry principles to reduce industrial waste
Bridging Tradition and Modern Science
Donkey-hide gelatin (Ejiao), a treasured ingredient in traditional Chinese medicine, has been revered for centuries for its nourishing properties. Yet, its modernization demands scientific rigor. Dong’e Chenkang’s R&D team, guided by Professor Wang, is redefining Ejiao’s potential by:
- Developing standardized peptide profiles (e.g., collagen tripeptides)
- Validating efficacy through in vitro/vivo absorption studies
- Expanding applications into functional foods and cosmeceuticals
Collaborative Roadmap
The visit culminated in a joint action plan:
- Phase I (2024): Establish a shared lab for enzyme stability testing.
- Phase II (2025): Co-publish research on Ejiao peptide bioavailability in international journals (e.g., Journal of Functional Foods).
- Long-Term Vision: Pioneer personalized Ejiao formulations leveraging metabolic profiling.
Professor Wang urged the team to “dare to innovate” in refining eco-friendly production systems, noting that “every 1% increase in enzymatic efficiency could reduce costs by 15% while boosting peptide purity.”
Dong’e Chenkang Pharmaceutical — Revitalizing Tradition with Cutting-Edge Science.